Scientific Contributors

Happy Neuron research activities are driven by a committed set of professionals with a background in Neurology, Neuropsychology, Cognitive Psychology and direct treatment of persons with age related brain decline.


Bernard Croisile

Bernard Croisile, M.D., Ph.D.

Chief Scientific Officer, Happy Neuron, Inc.

Publications
  • Croisile, B. (2007m). Alzheimer's disease and related diseases. Paris: Editions Larousse.
  • Croisile, B. (2007l). Memory in Richard Wagner's Tetralogy. In Memoirs of the Lyon Science, Fine Arts and Arts Academy (pp. 91-97). Editions de l'Académie Lyon.
  • Croisile, B. (2007k). Amnesic Mild Cognitive Impairment: An appointment at a memory clinic. Diagnosis, monitoring, and treatment of 90 patients. In Mild Cognitive Impairment. From normal brain aging to dementia (163-175). SOLAL, Collection Neuropsychologie, Marseille.
  • Croisile, B. (2007j). Oral and written language disorders at early stage Alzheimer's disease. Revue Neurologique, 163, 4S30.
  • Croisile, B. (2007i). Annotated Bibliographic News: Evaluating uncharacteristic demen-tia syndromes in PET with the PIB marker. Neurologies, suppl. XIV, 10, 7-8.
  • Croisile, B. (2007h). Annotated Bibliographic News: Early Alzheimer's disease diagnosis: optimizing coding specificities. Neurologies, suppl. XIV, 10, 5-6.
  • Croisile, B. (2007g). Cognitive examination in urban practice. La Revue du Praticien - Médecine Générale, 21(780/781), 932-935.
  • Croisile, B. (2007f). Memory complaints and memory disorders? Terminological thoughts. Mémoires-Actualités, 1, 1-3.
  • Croisile, B. (2007e). Appliance of the SNAB (Short NAming Battery) on 639 patients from a memory clinic. Revue de Gériatrie, 32, 343-354.
  • Croisile, B. (2007d). Annotated Bibliographic News: Dementias: 'Still PIB, always PIB!'
    Neurologies, suppl. VIII, 1, 9-10.
  • Croisile, B. (2007c). Annotated Bibliographic News: Dementias: 'For a few Teslas more! Direct visualization of amyloid plaques now conceivable via 7 Tesla MRI in Alzheimer's disease patients?' Neurologies, suppl. VIII, 1, 9.
  • Croisile, B. (2007b). Annotated Bibliographic News: Dementias: 'Mild Cognitive Impairment (MCI): Evolution of 4 clinical subtypes.' Neurologies, suppl. VII, 1, 9.
  • Croisile, B. (2007a). Annotated Bibliographic News: Dementias: 'Cerebral reserve & dementia. Cerebral reserve and cognitive decline.' Neurologies, suppl. VII, 1, 9.
  • Truchot, L., Costes, S.N., Zimmer, L., Laurent, B., Le Bars, D, Thomas-Antérion, C., Croisile, et al., (2007). Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment. Neurology, 69(10), 1012-1017.
  • Croisile, B., & Bonnefoy, M. (2007). Research and resources memory center of the Lyon Civil Hospices. DIRE, 92, 2.
  • Croisile, B., Astier, J.-L., & Beaumont, C. (2007). Calibrating the five-word-test on healthy controls. Revue Neurologique, 163(3), 323-333.
  • Croisile, B., Mollion, H., & Goni, S. (2007). Memantine effects in patients with mild to severe Alzheimer's disease with behavioral disorders. Summary of the French Speaking Days of Neurology, 2S42.
  • Noir, M., & Croisile, B. (2007). Get Your Brain in the Fast Lane: Turbocharge Your Memory with More Than 100 Brain Building Exercises. New York: McGraw-Hill.
  • Croisile, B., Astier, J.-L., & Beaumont, C. (2007). Administration of the SNAB (Short NAming Battery) to 349 patients from a memory clinic. Revue Neurologique, 163, 4S90-4S91.
  • Croisile, B., Astier, J.-L., Beaumont, C., & Mollion, H. (2007). The five-word-test in patients over 80 with Alzheimer's disease: Relevance of Total Weighted Score compared to Total Score. Revue Neurologique, 163, 4S91.
  • Truchot, L., Costes, N., Vighetto, A., Laurent, B., Lebars, D., Thomas-Antérion, C., Croisile, B., et al., (2007). Discrimination of Mild Cognitive Impairment from Mild Alzheimer's Disease by human in vivo serotonin metabolism exploration. Neurology, suppl. 1, 68(12), A61.
  • Croisile, B., Auriacombe, S., Pariente, J., & Polydor, J.-P. (2007). Vas-Cog 2007 – San Antonio (Texas) July 11-14, 2007. La Revue de Gériatrie, 32(9)
  • Croisile, B., Bélier, S., Allain, G., Noir, M., & Tarpin-Bernard, F. (2007). Improved cognitive performances for 85 assiduous subscribers to a cognitive training website. Revue Neurologique, 163, 4S131.
  • Croisile, B. (2006g). Starting dementias. Some thoughts. Psynergie, special issue "The beginnings", 13-18.
  • Croisile, B. (2006f). Memory stimulation. Which rational? Which exercises? Revue de Gériatrie, 31(6), 421-433.
  • Croisile, B. (2006e). Which patients should be offered memory rehabilitation? Neuronale, 26, 6-8.
  • Croisile, B. (2006d). XIXth day of the Alzheimer's disease research group in Marseille: Mild Cognitive Impairment. Revue de Gériatrie, 31(5), 353-355.
  • Croisile, B. (2006c). Annotated Bibliographic News: Dementias: 'The risk of dementia and cerebral vascular accidents throughout life.' Neurologies, Suppl. X, 9, 9-10.
  • Croisile, B. (2006b). Annotated Bibliographic News: Dementias: 'Subcortical dementias: History and personal thoughts.' Neurologies, Suppl. VIII, 9, 9.
  • Croisile, B. (2006a). Ten keys to memory. La Recherche, Les Dossiers, special issue: "Memory", 22, 8-13.
  • Desestret, V., Kaufman, M., Perret-Liaudet, A., Vighetto, A., Mercier, B., Croisile, B., et al. (2006). Correlation between 'hippocampic' memory and CRL tau protein in Alzheimer's disease. La Revue de Médecine Interne, 27 (Suppl. 3), S374-S375.
  • Croisile, B. (2005l). Communication, written language, and dementia. In Communication & dementias (pp. 83-103). SOLAL, Collection Neuropsychologie, Marseille.
  • Croisile, B. (2005k). A Short Naming Battery (SNAB) in memory clinics. La Revue Francophone de Gériatrie et Gérontologie, XII(120)
  • Croisile, B. (2005j). Annotated Bibliographic News: Dementias: 'Natural history of primary progressive aphasia.' Neurologies, Suppl. VII, 8, 5.
  • Croisile, B. (2005i). 30th anniversary of the MMSE! Neurologies, 8, 537-540.
  • Croisile, B. (2005h). Beyond ears: Memory and language. Journal of the French Society of Audiology, 2, 3-4.
  • Croisile, B. (2005g). Writing, aging, and Alzheimer's. Psychologie & Neuropsychiatrie du Vieillissement, 3(3), 183-197.
  • Croisile, B. (2005f). Memory: Know it well, use it well. Demain: Revue d'Information de la Mutuelle des Agents des Impôts, 73, 22-24.
  • Croisile, B. (2005e). Memory in the face of tests. Itinéraires Santé, 23, 4-5.
  • Croisile, B. (2005d). Dementias: Assessing behavior, independence, cognition & memory. Report: Evaluation in neurology. Useful scales & tests. Neurologies, 8, 129-132.
  • Croisile, B. (2005c). The role of a Neuropsychological Laboratory. Journal Interne du Groupement Hospitalier Est, 6, 2.
  • Croisile, B. (2005b). The secrets of memory. La Revue de la MTRL, 45, 4-8.
  • Croisile, B. (2005a). Memory. Retraite, (APICIL-MICIL group), 11, 12-13.
  • Etcharry-Bouyx, F., & Croisile, B. (2005). Dementias and syndromes. La Lettre du Neurologue, Oct. special issue, 22-24.
  • Bediou, B., Ryff, I., Vighetto, A., Milliery, M., Krolak-Salmon, P., & Croisile, B. (2005). Seeing MCI turn into dementia thanks to recognition of certain facial features.
    Revue Neurologique, 12(2), 4S113.
  • Croisile, B., Astier, J-L, et al (2005) Comparing results of the five-word-test of 18 anxiety, 18 control & 18 mild AD patients. Revue Neurologique, 12(2), 4S139.
  • Truchot, L., Vighetto, A., Costes, N., Lothe, A., Zimmer, L., Laurent, B., Croisile, B., & Krolak-Salmon, P. (2005). Diagnostic effectiveness of 18F-MPPF in PET in Alzheimer's disease. Revue Neurologique, 12(2), 4S96.
  • Milliery, M., Guerin, J., & Croisile, B. (2005). Study of a support group for families with neurodegenerative dementia patients: practice for 7 years and survey results.
    Revue Neurologique, 12(2), 4S139.
  • Noir, M., & Croisile, B. (2005). Dental Floss For The Memory: A Complete Program for Boosting Your Brain Power. New York: McGraw-Hill.
  • Croisile, B. (2004j). Your appointment with a neurologist. In Health as a goal: The keys to talking to doctors and helping you to take action (pp. 167-197). Editions Bayard-Notre Temps, Paris.
  • Croisile, B. (2004i). Artistic production and brain aging: Memory in Richard Wagner's Neuropsychologie works. In Neurodégénérescence et Vieillissement cérébral (185-196). SOLAL, Collection, Marseille.
  • Croisile, B. (2004h). Memory clinic: Adapted dementia treatment. Neurologies, 65, 456-459.
  • Croisile, B. (2004g). Dementias throughout the world. One disease, 5 cultures: solutions before disaster! La Lettre du Neurologue, 9, 18.
  • Croisile, B. (2004f). Mild Cognitive Impairment: 134 communications. La Lettre du Neurologue, 9, 7-9.
  • Croisile, B. (2004e). Memory clinics: Adapted dementia treatment. Repères en Gériatrie, 44, 6-9.
  • Croisile, B. (2004d). Neuropsychological thoughts: A trend, the dream of quick and effective! La Lettre du Neurologue, October spec. issue "Recent data on dementias", 14-15.
  • Croisile, B. (2004c). How are attention disorders and mnesic complaints linked? La Lettre du Neurologue, September spec. issue "Attention disorders and amnesic complaints", 3-6.
  • Croisile, B. (2004b). Knowledge gaps are nothing unusual! http://www.doctissimo.fr/html/psychologie/bien_memoriser/ps-8074-trous-de-memoire-normal-itw.htm.
  • Croisile, B., & Rothoft, J.-M. (2004b). Presentation and management of memory complaints in 726 general physicians: results of a questionnaire. Journal of Neurology, 251 (suppl. 3), 101.
  • Croisile, B., & Rothoft, J.-M. (2004a). Memory complaints in general practitioners: Presentation and management. La Revue de Gériatrie, 29(3), 179-188.
  • Croisile, B. (2004a). Alzheimer's disease: Easier detection, better treatment. TONIC – Le Journal des Hospices Civils de Lyon, 108, 10.
  • Croisile, B. (2003j). Maintaining a brain stimulating activity. In Larousse de la Santé au Féminin (pp. 265-267). Editions Larousse, Paris.
  • Croisile, B. (2003i). The female brain. Larousse de la Santé au Féminin (pp. 106-107). Editions Larousse, Paris.
  • Croisile, B. (2003h). Cerebral reserve, cognitive reserve: practical perspectives of a new concept. Actualités Innovations Médecine, 91, 40-44.
  • Croisile, B. (2003g). Cognitive aging: Cerebral reserve and cognitive reserve. Neuronale: Revue de Neurologie Comportementale, 1(12), 6-9.
  • Croisile, B. (2003f). Study of the five-word-test on 43 MCI subjects & 109 Alzheimer's disease patients. Revue Neurologique, 159(10), 5S69.
  • Croisile, B. (2003e). Editorial: "Don't forget about neuropsychology!" Neuronale: Revue de Neurologie Comportementale, 1(12), 3.
  • Croisile, B. (2003d). Neuropsychology: Multidisciplinary thoughts. Neurologies, 6(50), 193-194.
  • Croisile, B. (2003c). Cognitive aging: The future golden age of neurons? La Revue de Gériatrie, 28(5), 395-402.
  • Croisile, B. (2003b). After diagnosing, treating. Réminiscences - Maladie d'Alzheimer, 4.
  • Robert, P., Schuck, S., Dubois, B., et al. (2003b). Validating the short cognitive battery: Relevance for early detection of Alzheimer's disease and of depression in psychiatric practice. L'Encéphale, XXIX, 266-272.
  • Croisile, B. (2003a). Mild Cognitive Impairment: Diagnosis and actions to be taken in clinical practice. A study of 29 cases. La Revue de Gériatrie, 28(1), 17-28.
  • Robert, P., Schuck, S., Dubois, B., et al. (2003a). Screening for Alzheimer's Disease with the Short Cognitive Evaluation Battery. Dementia and Geriatric Cognitive Disorders, 15, 92-98.
  • Croisile, B., Astier, J.-L., & Beaumont, C. (2003). Predictive factors of MCI turning into Alzheimer's disease within 2 years. Revue Neurologique, 159, 2S144.
  • Croisile, B., Astier, J-L., & Beaumont, C. (2003). Calibrating & validating a short naming battery in clinical practice. Revue Neurologique, 159(10), 5S109-5S110.
  • Croisile, B. (2002g). The fascinating networks of memory. In Les Guides Notre Temps. Strengthen your memory (pp. 25-53). Editions Bayard-Notre Temps, Paris.
  • Croisile, B. (2002f). Primary progressive aphasia. In Dementias (pp 229-234). Doin Editeurs, Paris.
  • Croisile, B. (2002e). Dementia, Alzheimer's, what's new? La Lettre du Neurologue, July special issue, 20-21.
  • Croisile, B. (2002d). How can memory be trained? Relevance of a CD-Rom and board game. Soins Gérontologie, 7(36), 38-39.
  • Croisile, B. (2002c). Working methods. How to stimulate memory. Phosphore, 252, 92-93.
  • Croisile, B. (2002b). Mild Cognitive Impairment: a waiting room for Alzheimer's disease? La Revue de Gériatrie, 27(3), 189-194.
  • Croisile, B. (2002a). Anatomy & functional organization of memory. Neuronale, 4, 14-17.
  • Croisile, B., Tarpin-Bernard, F. & Noir, M. (2002). Experiment of a cognitive training website for seniors. Revue Neurologique, 158, 2S126.
  • Croisile, B. & Weisz, S. (2002). How to improve your memory. Management, 86, 67-74.
  • Croisile, B. (2001c). Current treatments for Alzheimer's Disease. Abstract Neuro, 13, 18-21.
  • Croisile, B. (2001b). Test your memory abilities on the Internet. Horizons, 9, 5.
  • Croisile, B. (2001a). Cognitive functions and aging. Retraite, 2, 6-9.
  • Croisile, B., Astier, J.-L., & Girard, C. (2001). Using the five-word-test in 21 MCI and 49 control subjects. Revue Neurologique, 157, 4S60-4S61.
  • Croisile, B., & Noir, M. (2001). Neurons for our future. Le Spectacle du Monde, 10(472), 84-87.
  • Croisile, B., & Godefroy, O. (2001). Vascular dementias. La Lettre du Neurologue. 29-32.
  • Croisile, B. (2000b). Memory: Understanding how it works and its disorders (2nd part).
    La Revue de la MTRL, 25, 8-9.
  • Croisile, B. (2000a). Memory: Understanding how it works and its disorders (1st part).
    La Revue de la MTRL.
  • Thomas-Antérion, C., Croisile, B., & Moreaud, O. (2000). Alzheimer's disease: Evolution of our understanding. La Lettre du Neurologue, 4-8.
  • Croisile, B. (1998). Memory disorders. TONIC: Le Journal des Hospices Civils de Lyon, 86, 9-11.
  • Hibert, O., Laurent, B., Croisile, B., et al. (1994). Memory testing video simulation.
    Annales de Réadaptation et de Médecine Physique, 37, 265-274.
  • Trillet, M., & Laurent, B. (1988). Memory and amnesias. Paris: Editions Masson.
  • * NOTE: Dr. Croisile's scientific publications include over 200 peer-reviewed articles, books, book chapters, and book collaborations dating from 1984. His complete bibliography is predominantly comprised of writings on neurological disease, neuropsychological disorders, and healthy aging. Major topics include memory and memory disorders, cognitive assessment and training, dementia and Alzheimer's Disease, Mild Cognitive Impairment and brain imaging. The abridged bibliography above represents the fraction of his work most directly pertinent to Happy Neuron, Inc. and its subscribers.

Dr. Croisile is a respected neurologist and neuropsychologist with an international reputation for his research on aging and cognition. He was the recipient of the Alzheimer's Disease Parke-Davis Award in 1998 and has written several hundred peer-reviewed articles, papers, and book chapters on aging and cognition. These represent only a fraction of his scientific contributions. Further, he has spoken at hundreds of professional conferences on the prevention of dementia and age-related cognitive decline. Dr. Croisile has been the Chair of the Neuropsychology Laboratory, Cognitive Functions, Language and Memory, at the Neurological Hospital of Lyon France, since 1992. He received his M.D. and certification in Neurology from Lyon Hospitals and his Neurosciences Specialty degree and Ph.D. in Neuropsychology from University Claude Bernard in Lyon, France.

Robert Bender

Robert Bender, M.D.

Geriatrician

Assistant Medical Director, The Johnny Orr Memory Center And Healthy Aging Institute.

Publications
Publications:
  • Bender, R. (2006). A Multifactorial Approach to Cognition in Patients with Dementia. The Aging Brain, 2nd Edition.
Research Activities:
  • “Wellness and Lifestyle Change in Seniors”. Sponsored project, Centers for Disease Control, 2007.
  • “Brain Wellness”. A multi-factorial approach to patients with Alzheimer’s disease. Sponsored project, Centers for Disease Control, 2006.
  • “Preventive Medicine and Wellness in the Nursing Home”. Sponsored project, Centers for Disease Control, 2004.
  • “Hypothyroidism in the Elderly”. Presented at the American Academy of Family Physicians Scientific Assembly, Kansas City, Mo, 1983. First prize for research by a practicing family physician.

Dr. Robert Bender is a Board Certified physician in both Family Practice and Geriatrics who lives and practices in Des Moines, Iowa. He has served on the faculties of Mercy-Mayo Hospital, where he developed and directed the Family Practice residency from 1994-1998, and Iowa Methodist Medical Center, where he was Director of Geriatrics for the Internal Medicine Residency from 1998-2006. He has conducted several research projects on brain aging, brain wellness and Alzheimer's Disease, sponsored by the U.S. Centers for Disease Control. In 2005, he was a delegate of the American Geriatrics Society to the White House Conference on Aging. He currently directs the Johnny Orr Memory Center in Des Moines.

Michel Noir

Michel Noir, Ph.D.

Chief Executive Officer, Happy Neuron, Inc.

Post-graduate diploma in Cognitive Psychology

Doctorate in Education Science

Dr. Noir is a cognitive psychologist with a creative background, including having authored 15 books. He received his Graduate Diploma, Advanced Graduate Diploma, and Master's in Public Law from Paris Law Faculty. He later received an Advanced Graduate Diploma in Political Science and a Ph.D. in Educational Sciences from Lyon II University.

Franck Tarpin-Bernard

Frank Tarpin-Bernard, Ph.D.

VP Engineering

Publications
  • Tarpin-Bernard, F., Samaan, K. & David, B.T. (2007). A Method for building adaptable software that respect usability. In A., Seffah, J., Vanderdonckt, & M., Desmarais (Eds.). Computer Human Interaction and Software Engineering, 2. Berlin: Springer Verlag.
  • Sghaier, A., Prévôt, P., & Tarpin-Bernard, F. (2007). Towards a Generic Environment for the Design of Serious Games. Proceedings of Learning with Games 2007.
  • Tarpin-Bernard, F. & Habieb-Mammar, H. (2005). Modeling Elementary Cognitive Abilities for Adaptive Presentation of Hypermedia. User Modeling and User-Adapted Interaction (UMUAI). The Journal of Personalization Research, 15(5), 459-495.
  • Habieb-Mammar, H., & Tarpin-Bernard, F. (2004). CUMAPH: Cognitive User Modeling for Adaptive Presentation of Hyper-documents. Proceeding of the Third International Conference on Adaptive Hypermedia and Adaptive Web-Based Systems (AH 2004) (LNCS3137).
  • Habieb-Mammar, H., Tarpin-Bernard, F., & Prévôt, P. (2003). Adaptative presentation of multimedia interface, case study: “Brain Story” Course. Proceedings of UM 2003, the 9th International Conference on User Modelling (LNCS2702).
  • Habieb-Mammar, H., & Tarpin-Bernard, F. (2002b). How to Incorporate Cognitive Styles into Adaptive Multimodal Interfaces. Proceedings of EDMEDIA 2002, World Conference on Educational Multimedia, Hypermedia and Telecommunications.
  • Habieb-Mammar, H., & Tarpin-Bernard, F. (2002a). Cognitive Styles and Adaptive Multimodal Interfaces. Proceedings of CogSci’2002, the 24th annual meeting of the Cognitive Science Society.
  • Tarpin-Bernard, F., Habieb-Mammar, H., Croisile, B., & Noir, M. (2001). A supervised Program for Cognitive e-Training. Proceedings of WebNet’2001, World Conference on Web technologies.

Dr. Franck Tarpin Bernard has been instrumental in making the science and creativity of scientific game designs come alive as interesting, fun, challenging multi-media games with performance tracking and coaching. Dr. Tarpin-Bernard is a Professor in Computer Science at the National Institute of Applied Science of Lyon and has published numerous peer-reviewed journal papers and book chapters. He graduated first in his class in engineering from Ecole Centrale de Lyon and later received a Ph.D. in computer engineering, also from Ecole Centrale de Lyon.

Diana Miner

Diana Miner, M.A., M.S.

Neuropsychology Intern, Yale University, School of Medicine, Dept. of Psychiatry

Publications
  • Miner, D. (June, 2007). Cognitive correlates of the MMPI-2 depression scales in a heterogenous neuropsychiatric sample. Doctoral Dissertation, Pacific Graduate School of Psychology. (Manuscript for publication in preparation).

Originally from Montreal, Canada, Diana Miner is a doctoral candidate in neuropsychology. She held a pre-doctoral research fellowship at Stanford University Medical School and received further training in neuropsychology at the Palo Alto VA Medical Center.
She completed a Masters in Science degree in 2005 and recently completed her doctoral dissertation, entitled "Cognitive correlates of the MMPI-2 Depression Scales". She is currently a Research Scientist and Scientific Product Manager at Happy Neuron Inc. At Happy Neuron, Diana's responsibilities include oversight of scientific validity testing of cognitive training programs, editorial review of scientific content, collaboration with national and international research groups and scientific investigation of selected topics in cognitive training and cognitive reserve.